Tohru Yamada, PhD, is Associate Professor in the Departments of Surgery and Biomedical Engineering in the Colleges of Medicine and Engineering. His research is focused on brain tumors. His area of research interest and expertise is the discovery and development of a new class of peptide-based carriers and anticancer agents for therapeutic and imaging agents targeting cancers in the basis of molecular biology, protein/peptide chemistry, cell biology and basic and translational cancer biology. For his innovative work using new types of agents for cancer therapy and imaging, he was elected a 2023 Fellow of the National Academy of Inventors. He has been actively involved in developing novel anionic amphipathic cell penetrating peptide p28, identified from a copper-containing redox protein azurin secreted by Pseudomonas aeruginosa. A Phase I clinical trial of p28 as an anti-cancer agent on adult advanced solid tumors was completed, and also completed was another Phase Ia/b clinical trial on pediatric central nervous system (CNS) tumors supported by the National Cancer Institute and the Pediatric Brain Tumor Consortium.
Tohru Yamada, PhD
Associate Professor
Surgery
Medicine
Research Program
Translational Oncology Program (TO)
Phone: 312-413-1156
Email: [email protected]
