Maria Barbolina, PhD

Our main research interests are centered on identifying and characterizing novel mechanisms regulating ovarian carcinoma metastasis. The goal of these studies is to identify novel drug-targetable vulnerabilities in ovarian carcinoma and to validate potential new drug targets in preclinical models of the disease. We combine a broad range of biochemical, cell and molecular biology assays, as well as animal models to address this unmet need. We are also interested in mechanisms regulating neurodegeneration and memory/learning. Mechanistic characterization of common molecular mechanisms governing neurodegeneration and cancer enables us to repurpose cancer drugs for neuroscience and vice versa.