Jing Liu, PhD

Title & Department

Associate Professor

Surgery

College of Medicine

Research Program

Cancer Biology (CB)

Phone: 312-355-0073

Email: jinglius@uic.edu

Jing Liu, Ph.D. (Associate Professor, Surgery, Cancer Center) studies the molecular mechanisms that govern inflammation in pulmonary diseases, including COPD, asthma, and ARDS. Inflammation is part of the host defense system against invading pathogens, but deregulated inflammation is also known to play a crucial role in the pathology of various diseases, from inflammatory lung diseases to cancer.The molecular mechanism that controls inflammation and the pathological impact of deregulated inflammation on human diseases are incompletely understood. Our work discovered that the Myc-interacting zinc finger protein 1 (Miz1) plays a central role in signaling the resolution of inflammation through epigenetic regulation of C/EBPd and/or NF-kB activity by histone modifications, with implication in COPD.Additionally, our work uncovers the stress-activated protein kinase JNK2 as a fine tuner of inflammasome through promoting mitophagy, thereby maintaining immune homeostasis.

Education

PhD, Nanfang Medical University, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Disease Focus

Lung

Published Research

PubMed Search

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