A Nature Communications paper from researchers at the University of Illinois Chicago, including University of Illinois Cancer Center member Jalees Rehman, MD, has identified a process by which enzymes can help prevent heart damage in chemotherapy patients.
The enzymes are normally found in a cell’s mitochondria, the powerhouse that produces energy. But when heart cells are put under stress from certain types of chemotherapy drugs, the enzymes move into the cell’s nucleus, where they are able to keep the cells alive.
Rehman, head of the UIC Department of Biochemistry and Molecular Genetics, is co-senior author on the paper with Sang Ging Ong, PhD, assistant professor of pharmacology and medicine in the UIC Department of Pharmacology and Regenerative Medicine. At the Cancer Center, Rehman is part of our Cancer Biology research program.
More in Nature Communications
Read about the paper at UIC Today.