University of Illinois Cancer Center member Alexandra Naba, PhD, collaborated with researchers at the University of Oulu in Finland on a new manuscript published in the Journal of Cell Science on a suite of tools to annotate and quantify extracellular matrix (ECM) molecules in a broad range of -omic datasets ranging from genomic to RNA-Seq and scRNA-Seq to proteomic.
Naba’s objective is to design user-friendly and open-access tools and resources to advance ECM research and accelerate ECM biomarker discovery efforts.
Part of the Cancer Center’s Cancer Biology research program, Naba pioneered the application of proteomics to study the ECM, the ensemble of proteins that make up the scaffold organizing cells, tissues and organs. She is also founder of the Matrisome Project and the database MatrisomeDB, two major resources for ECM research used worldwide.
In Journal of Cell Science
Naba and Valerio Izzi, PhD, of the University of Oulu, are co-corresponding authors of the manuscript “Matrisome AnalyzeR: A suite of tools to annotate and quantify ECM molecules in big datasets across organisms.”