National Institutes of Health Funding

Funding Opportunity: National Institutes of Health

National Institutes of Health (NIH) funding opportunities that may be of interest to University of Illinois Cancer Center members.

Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 – Clinical Trial Optional)

Application Date: 02/02/2025, 06/05/2025, 10/05/2025

Purpose: The purpose of this initiative is to advance the science and implementation of innovative multi-level health care research for older adults from populations that experience health disparities. The initiative will support research designed to (1) gain a better understanding of appropriate screening, diagnostic, and clinical care guidelines in a primary care setting, (2) explore shared decision-making that is needed to enhance care planning and patient agency between clinicians and care teams with the older adult and their caregiver(s), and (3) identify effective strategies for care coordination.

Underrepresentation of older adults, especially those over the age of 75, in clinical research.
Age-dependent variations in sensitivity and/or specificity of screening and/or diagnostic tests.
Screening tests for which diagnostic and/or treatment benefit is unclear after a certain age, or within the context of health status, quality of life, and/or projected life expectancy.
Screening tests recommendations that consider patient preferences and weigh benefits versus risks/ harms.
Symptoms and signs that are different from the clinical profiles observed in younger populations.
Delayed recognition of health conditions by patients and caregivers/family members due to attribution of symptoms as part of the normal aging process.
Family dynamics, built environment, and sociocultural environment factors that influence optimal care and quality of life.
Diagnostic protocols or guidelines that create gaps in care delivery.
Diagnostic, treatment, and continuity of care complexities associated with multiple coexisting chronic conditions.
Side effects and adverse events associated with complex pharmacological therapy.
Unfamiliarity or lack of proficiency in key cultural factors across different levels in the healthcare continuum and across various stages of the aging continuum.
Limited health system resources and infrastructure, and health care policies that may limit coverage eligibility or access to optimal care and health equity.
Lack of shared decision-making that is guided by principles of aging with dignity, self-determination, and autonomy.

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 (P50 Clinical Trial Required)

Application Dates: 09/25/2024 & 01/25/2025 & 05/25/2025
Optional Letter of Intent: Due 30 days before the application due date.
Purpose: Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). Based on the research proposed, applications may be jointly funded with the National Institute of Dental and Craniofacial Research (NIDCR). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a related group of cancers. For this NOFO a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent or cancers sustained and promoted by the dysregulation of a common signaling pathway. In addition, a SPORE may focus on cross-cutting themes such as pediatric cancers or cancer health disparities. The research supported through this program must be translational and must stem from research on human biology using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant.

Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed)