We investigate regulation mechanisms of vascular functions, especially angiogenesis and vascular leakage in cancer metastasis. Our primary focus is intracellular molecule trafficking by kinesin family molecular motors. Our strategy regulating trafficking of a receptor for growth factor effectively suppresses angiogenesis, vascular leakage, and cancer metastasis. We will investigate the mechanisms further and develop this strategy for preventing cancer metastasis.

Kaori Yamada, PhD
Assistant Professor
Department of Pharmacology and Regenerative Medicine
College of Medicine
Research Program
Cancer Biology (CB)
Phone: (312) 996-1906
Email: horiguch@uic.edu