Dr. Jonna Frasor is a Professor in the Department of Physiology and Biophysics. Her research is focused on the crosstalk between estrogen and NFkB, endocrine therapy resistance, lipogenesis, metabolism, tumor metastasis and dormancy. She has over 15 years of experience in the estrogen receptor field, with particular interest in mechanisms underlying estrogen-dependent breast cancer biology. Dr. Frasors graduate research was under the direction of Dr. Geula Gibori and was focused on the mechanisms by which prolactin regulates estrogen receptor function. As a postdoctoral fellow, she worked in the laboratory of Dr. Benita Katzenellenbogen, where she had studied ER-dependent gene regulation in response to agonists and Selective Estrogen Receptor Modulators, such as tamoxifen and raloxifene. Dr. Frasor has been a PI of her own independent research lab since 2005. She has extensive experience studying the effects of hormones, growth factors, and inflammatory cytokines in breast cells and tissues, both normal and cancerous.Her research is focused on crosstalk between estrogen and NFkB, endocrine therapy resistance, lipogenesis, metabolism, tumor metastasis and dormancy.