Constance Jeffery, PhD

Associate Professor

Department of Biological Sciences

College of Liberal Arts and Sciences

Research Program

Cancer Biology (CB)

Phone: 312-996-3168

Email: [email protected]

The Jeffery Lab studies the connections between protein sequences, structures, and functions. We use a combination of biochemical and biophysical methods, computer-based bioinformatics, and X-ray crystal structural analysis. Current research includes the effects of cancer and inflammatory bowel disease (IBD) associated mutations on protein structure and function. The lab also studies the structures and functions of moonlighting proteins and pseudoenzymes and their roles in metabolism, signaling pathways, interactions with extracellular matrix, and invasion and metastasis.


PhD, University of California at Berkeley

Disease Focus

Gastrointestinal; Colorectal

Research Keywords

Protein Structure; Protein Function; Moonlighting Proteins; Pseudoenzymes; Metamorphic Proteins; Protein Evolution; Disease-associate Mutations; Inflammatory Bowel Disease

Published Research

PubMed Search

Other Link(s)

Department Webpage

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