Dr. Bin He is an Associate Professor in the Departments of Microbiology and Immunology at the University of Illinois College of Medicine. His laboratory focuses on developing engineered herpesvirus (HSV) for cancer therapy, and viral vaccines. With a focus on cytokines and inflammation, one program investigates viral gene functions. Another program studies innate immunity in pathological conditions. Their contributions to sciences include: (i) virus-host interactions pertinent to cytokine responses. These studies laid out the scientific basis for oncolytic HSV recently approved by FDA for cancer therapy; (iii) Dendritic cells (DC) in virus infection. These studies provide an insight into virus-DC interactions, opening an avenue to develop viral vaccines; (iii) Inflammation and enteroviruses. This body of work has established the groundwork for potential therapeutic targets.His research is focused on engineering HSV for cancer therapy and viral vaccines.