Biostatistics Shared Resource Core

Welcome to Biostatistics Shared Resource Core of University of Illinois Cancer Center

infographic showing the tools used by the Biostatistics Core at the University of Illinois Cancer CenterIn February 2020, the Biostatistics Shared Resource Core (BSRC) of University of Illinois Cancer Center was established under the direction of Zhengjia (Nelson) Chen, PhD. BSRC is composed of a group of faculty and dedicated staff.

The BSRC plays a pivotal role in the success of cancer research at the UI Cancer Center by providing state-of-the-art services. BSRC collaborates with all UI Cancer Center members and participates in cancer research across the 3 research programs, Cancer Biology, Translational Oncology and Cancer Prevention & Control of the cancer center. The BSRC is recognized as an essential element of research infrastructure at the UI Cancer Center by way of collaboration and consultation with UI Cancer Center investigators in the design, conduct and analysis of cancer-related clinical, preclinical, epidemiological, and community based investigations. These collaborations lead to the application and development of innovative statistical methodology and summarization of results to address cancer research. Providing biostatistics services within a single shared resource offers UI Cancer Center investigators a single collaboration site during all stages of their research. BSRC facilitates the translation of research findings into clinical trials and disseminates the new knowledge to support the planning new collaborative research projects. BSRC also supports UI Cancer Center’s education mission by providing journal clubs and training workshops as well as statistical consultation and collaboration for trainees and early career UI Cancer Center members.

Biostatistics support:
Services have been focused on statistical consultation and collaboration on the design, conduct, analysis and interpretation of all research activities of University of Illinois Cancer Center.  To request support from BSRC, please complete and submit this request form. Services include:

  • Provide consultation and collaboration regarding all types of study design (e.g., validity of design, feasibility of meeting objectives, sample size, projection of study duration).
  • Design clinical trial with adaptive and sequential design
  • Clinical trial and study protocol development
  • Statistical monitoring and assessing the progress of studies
  • Data analysis, assistance in manuscripts and presentations
  • Develop novel biostatistics and bioinformatics methods
  • Review proposals for clinical cancer-related studies within the context of the clinical trials review committee

 Data Management:

The BSRC statistical data management operations are responsible for the support of research databases including OnCore and eCRFs forms. The BSRC also incorporates REDCap in its support for studies such as population-based observational studies and hospital chart review data. Statistical data managers routinely perform data extractions, quality control and create analysis datasets.

Scientific Review for Cancer Center:

By evaluating the statistical feasibility of each proposed project, particularly on sample size, power and study design, the BSRC members are an integral part of Clinical Protocol and Data Management (CPDM), Protocol Review and Committee (PRC), the Data and Safety Monitoring Committee (DSMC), and service based programs.

Education and Training:

The BSRC members actively participate in the education and training of cancer investigators. BSRC also provide monthly seminar on the state-of-the-art approaches for cancer research for graduate students, oncology residents, fellow and UICC members.

Cancer Center members:

Our BSRC is dedicated to the cancer center members. Priority for the BSRC services is given to the cancer investigators with peer-reviewed funding, extramural grant submissions and pending manuscript or abstract submissions. Please fill in the request form to schedule a consultation.

Our BSRC does not implement charge back system for cancer center members. The BSRC provides free assistance on preliminary data analysis for grant applications, grant statistical support, investigator-initiated clinical trial design, protocol preparation and project planning. Providing a no-cost service for conceptualization of grant design and methods encourages members to consider applying for extramural grant funding and expedites the statistical planning of cancer-focused research. BSR members on funded grants or contracts are covered by appropriate levels of percent effort on collaborative work. It is a common criteria to cover a faculty biostatistician at least 5% effort on a R01, and 3% at R21, R03, ACS, DOD, etc. It is also required to budget 3% effort for Biostatistician in a Sponsor or contract supported clinical trial with more than 20 patients, or 5% in one with more than 100 patients, respectively.

PUBLICATION ACKNOWLEDGMENT POLICY

The National Cancer Institute requires that publications acknowledge the University of Illinois Cancer Center Biostatistics Shared Resource Core (BSRC) and it is tracking compliance. If University of Illinois Cancer Center BSRC provided data, designed the study, performed analyses, provided results used in your publication, and/or provided any systems or services that were used for the work that resulted in your publication, please include the following statement in the acknowledgment section of your publication(s):
Research reported in this publication was supported in part by the University of Illinois Cancer Center Biostatistics Shared Resource Core (BSRC).

Core Director:

Zhengjia (Nelson) Chen PhDNelson Chen close up with face in focus and book shelves on background.

Associate Professor of Biostatistics
Biostatistics Shared Resource of University of Illinois Cancer Center
818 South Wolcott Avenue, Room 524, Chicago, IL 60612
Phone: (312)-996-6027 | Email: znchen@uic.edu


Faculty Biostatistician:

Li Liu PhDJing Liu close up with face in focus and white background.

Associate Professor of Biostatistics
1603 W. Taylor St. SPHPI 979, Chicago IL 60612
Phone: (312) 996-0399 | Email: liliu@uic.edu


Core Coordinator and BSRC Contact:

Daisy Cintron, MA

Biostatistics Shared Resource of University of Illinois Cancer Center
818 South Wolcott Avenue, Room 506, Chicago, IL 60612
Phone: (312)-996-6369 | Email: dcintron@uic.edu


Director of Oncology Informatics:

Sandeep Kataria close up with face in focus.Sandeep Kataria

818 S. Wolcott Ave., Room 426, Chicago, IL 60612
Phone: 312-413-5960 | Email: skataria@uic.edu

For informatics needs contact Sandeep Kataria directly.