Newly Activated Clinical Trials

Monday, February 23, 2026

This is a listing of clinical trials recently activated by the University of Illinois Cancer Center Clinical Trials Office for patient enrollment. Click the study links below to learn details regarding the studies on clinicaltrials.govYou can also search for other clinical trials on our website. For more information or questions about a study, email cancertrials@uic.edu or call 312-355-5112.


Protocol Title: FURMO-006: A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer With Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)


Protocol Title: CTIU2317-A082304-S2402: Perioperative Versus Adjuvant Systemic Therapy in Patients with Resectable Non-Small Cell Lung Cancer - PROSPECT LUNG


Protocol Title: IRB24-1729:  A Feasibility Trial of LHRH Agonist Discontinuation In Elderly Prostate Cancer Patients 


Protocol Title: A032303: Gemcitabine Alternating With INtravesical BCG Randomized Against BCG Alone for Patients With Recurrent High Grade Non-Muscle Invasive Bladder Cancer (GAIN-BCG)


Protocol Title: ARTEMIDE-Gastric01: A Randomized, Phase III Study of Rilvegostomig in  Combination with Fluoropyrimidine and Trastuzumab Deruxtecan Versus Trastuzumab, Chemotherapy, and Pembrolizumab for the First-Line Treatment of HER2-Positive Gastric Cancer


Protocol Title: A012303: Shortened Duration of Adjuvant Therapy in Patients with Early-Stage HER2+ Breast Cancer Who Achieve pCR After Neoadjuvant Chemotherapy with HER2 Blockade


Protocol Title:  ACNS2321: A Phase II Trial Evaluating Chemotherapy followed by Response Based Reduced Radiation Therapy for Patients with Central Nervous System Germinomas