Dr. Srilata Bagchi
Dr. Srilata Bagchi’s research focuses on better understanding the development of human papillomavirus (HPV) associated cancers at the molecular level. Her analysis involves studies in two different types of HPV-associated cancers, human cervical cancers and Oral and Head and Neck cancers, HNSCC. She analyzes how these viral oncoproteins modify the key cellular tumor suppressor proteins to initiate and sustain tumorigenesis. Another focus of Dr. Bagchi’s research is to study the role of DNA damage and Repair processes in the development of cancer. DNA damage in somatic cells is one of the main causes of aging, cellular senescence, and development of genetic diseases, including cancer. Dr. Bagchi, in collaboration with Dr. Pradip Raychaudhuri of the Department of Biochemistry and Molecular Genetics at UIC, analyzes how the DNA damage, induced by tobacco metabolites, leads to the development of lung cancer and HNSCC.