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Viswanathan Natarajan, PhD
Cancer Biology Research Program
Professor
Division of Pulmonary, Critical Care, Sleep and Allergy
College of Medicine
Email: visnatar@uic.edu
Viswanathan Natarajan, PhD, is Professor of Medicine and Pharmacology at the University of Illinois College of Medicine at UIC in the Division of Pulmonary, Critical Care, Sleep and Allergy. He is a basic/translational research scientist, and the overall goal of his research is to understand molecular mechanisms and signaling pathways mediating lung inflammation and injury, and lung cancer. He is focused on developing novel therapeutic agents to ameliorate or block lung tumor growth and metastasis and pulmonary leak/lung edema, and restore barrier integrity. His lab has identified lysocardiolipin acyltransferase (LYCAT), a cardiolipin remodeling enzyme in the mitochondria, as a key regulator of Non-Small Cell Lung Cancer (NSCLC) migration and invasion in vivo and in vitro. They have developed peptide inhibitors to block LYCAT activity and arrest NSCLC motility and invasion in animal models of lung cancer. He has been continuously funded by the National Institutes of Health/National Heart, Lung, and Blood Institute since 1993 to work on mechanisms of lung pathologies, including lung inflammation, sepsis and pulmonary hypertension.
Education
- PhD, Indian Institute of Science, Bangalore
Published Research
Other Link(s)
Research Focus
- Translational Oncology
- Pharmacology
- Lung Cancer
- NSCLC
- Translational Research
- Signaling Pathways
- Molecular Mechanisms
- Cancer Biology