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Kostandin Pajcini, PhD
Cancer Biology Research Program
Associate Professor
Department of Pharmacology and Regenerative Medicine
College of Medicine
Email: kvp@uic.edu
Kostandin Pajcini, PhD, is Associate Professor of Pharmacology at the University of Illinois College of Medicine at UIC. His research focuses on bringing together the highly conserved cell-cell signaling mechanisms to the study of hematopoietic development and disorders. A key area of his work is the role of Notch signaling in the interactions of hematopoietic stem cells with the fetal liver and adult bone marrow niches because aberrant Notch signaling leads to T-cell acute lymphoblastic leukemia (T-ALL). The focus is on how to specifically target hyperactive Notch mutations in T-ALL by identifying novel gene targets and by directly targeting the Notch receptor mutations through gene editing.
Education
- PhD, Stanford University
Other Link(s)
Research Focus
- Cancer Biology