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Jing Liu, PhD

Translational Oncology Research Program

Assistant Professor
Department of Surgery
College of Medicine

Email: jinglius@uic.edu

Jing Liu, PhD, is Assistant Professor in the Department of Surgery at the University of Illinois College of Medicine at UIC. She studies the molecular mechanisms that govern inflammation in pulmonary diseases, including COPD, asthma, and ARDS. Inflammation is part of the host defense system against invading pathogens, but deregulated inflammation is also known to play a crucial role in the pathology of various diseases, from inflammatory lung diseases to cancer. The molecular mechanism that controls inflammation and the pathological impact of deregulated inflammation on human diseases are incompletely understood. Our work discovered that the Myc-interacting zinc finger protein 1 (Miz1) plays a central role in signaling the resolution of inflammation through epigenetic regulation of C/EBPd and/or NF-kB activity by histone modifications, with implication in COPD.Additionally, our work uncovers the stress-activated protein kinase JNK2 as a fine tuner of inflammasome through promoting mitophagy, thereby maintaining immune homeostasis.

Language : English

Education

PhD, Nanfang Medical University, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Published Research

Research Focus

Translational Oncology
Tumor Microenvironment
Immunotherapy
Lung
Gastrointestinal
Colorectal

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Jing Liu, PhD

Translational Oncology Research Program

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