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Amy Kenter, PhD

Cancer Biology Research Program

Professor
Department of Microbiology and Immunology
College of Medicine

Email: star1@uic.edu

Amy Kenter, PhD, is a Professor in the Department of Microbiology and Immunology at the University of Illinois College of Medicine at UIC. Her research is focused on immunoglobulin gene rearrangements and the role that Mbd4 has in somatic hypermutation and cancer. Her laboratory has been focused on the molecular mechanism of class switch recombination (CSR) for many years. They designed an assay for double strand breaks in S regions and detected these breaks in S regions of B cells induced for CSR. Her lab discovered transcription factors bound to S region which may modulate isotype specific recombination. They also have examined the chromatin structure of the Igh locus in the context of CSR. These studies have revealed that chromatin accessibility and transcription are linked and that RNA polymerase pausing is intrinsic to these processes. They developed evidence that the Mbd4 is a critical regulator of CSR.

Language : English

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PhD, Albert Einstein

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Amy Kenter, PhD

Cancer Biology Research Program

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