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Obesity and Breast Cancer: How Obesity Changes the Microenvironment

January 11 at 10:00 am - 11:00 am

Lisa Arendt, DVM, PhD
Assistant Professor, Department of Comparative Biosciences, School of Veterinary Medicine
University of Wisconsin-Madison

 

Obesity is a significant risk for breast cancer in postmenopausal women. Regardless of menopausal status, obesity increases the growth of clinically more aggressive breast tumors. Using a novel patient-derived xenograft model as well as a high fat diet model of obesity, we investigated how obesity-induced inflammation enhances aggressive cells within primary tumors, promotes fibrosis within the tumor microenvironment and increases metastasis. Targeting inflammation may significantly enhance therapeutic response in obese breast cancer patients.

Details

Date:
January 11
Time:
10:00 am - 11:00 am

Venue

College of Medicine, Moss Auditorium (Room 1020)
909 S Wolcott Ave
Chicago, IL 60612
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