Rana lab hopes third line medication could be charm for pancreatic cancer patients

Long-term treatment of pancreatic cancer using the chemotherapy drug gemcitabine leads to extensive reprogramming of the immune microenvironment, sensitizing tumors to the benefit of a multi-drug immunotherapy regimen, according to new research from the University of Illinois College of Medicine. Pancreatic ductal adenocarcinoma (PDAC) – the most common form of pancreatic cancer – is projected to be the second leading cause of cancer-related death in the United States, with an overall five-year survival…

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Phase 1 human trials suggest UIC-developed breast cancer drug is safe, effective

A new type of breast cancer drug developed by University of Illinois Cancer Center members Debra Tonetti and Gregory Thatcher can help halt progression of disease and is not toxic, according to phase 1 clinical trials. The drug is specifically designed for women whose cancer has stopped responding to hormone therapy. The results are published in the journal Breast Cancer Research and Treatment. Breast cancer affects one in eight women in the United…

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Quigley featured in Big Ten CRC newsletter
Dr. John Quigley

Quigley featured in Big Ten CRC newsletter

University of Illinois Cancer Center member John Quigley, MD, was featured in June’s Big Ten Cancer Research Consortium’s newsletter highlighting his abstract presentation during the American Society of Clinical Oncology’s ASCO20 Virtual Scientific Program, which included more than 250 oral abstract presentations and 2,500 poster presentations from 24 disease-based and specialty tracks. The BTCRC-AML17-113 poster provides safety and efficacy data for the Phase 1b study of gemtuzumab ozogamicin (GO) and venetoclax in patients…

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Liquid biopsies using urine and plasma could be the future of lung cancer screening

University of Illinois College of Medicine researchers, led by Alicia Hulbert, have developed an epigenetic-based approach that helps detect non-small cell lung cancer through liquid biopsies using urine and plasma. In recent years, scientists have been using new techniques such as methylation-specific PCR – one of the most commonly used methods for epigenetic studies which assesses the changes in DNA expression without altering its sequence. In a new paper published in the journal…

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MD/PhD student aspires to lessen severity of pancreatic cancer

Daniel Principe is working to make the words ‘pancreatic cancer’ less foreboding. “Pancreatic cancer has a dismal prognosis, with a median survival time of six to 12 months,” said Principe, a MD/PhD student at the University of Illinois College of Medicine who has received a Ruth L. Kirschstein National Research service F30 award from the National Cancer Institute (NCI) to fund a research project on the disease. “This is largely attributed to the…

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Khan presented with grant from Leukemia Research Foundation

Irum Khan, assistant professor of hematology/oncology at the University of Illinois College of Medicine and a member of the University of Illinois Cancer Center, was one of 12 scientists in the United States chosen to receive a grant from The Leukemia Research Foundation. Dr. Andrei Gartel, associate professor, and member of the UI Cancer Center is co-Investigator on this study. Khan, MD, will receive $100,000 in funding year 2019-2020 to conduct research on…

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Hyundai bestows grant to fight pediatric cancer to UI Health

A unique paint job adorned the 2019 Hyundai Santa Fe parked in the University of Illinois at Chicago lot, one that can’t be found on any other car. It was decorated with colorful handprints from children suffering from cancer. Pediatric cancer patients treated at the University of Illinois Health Science System dipped their hands in blue, green and red paint last week and left a lasting impression on the white car during a…

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Moore receives AACP award for best paper

A team of University of Illinois at Chicago researchers that included University of Illinois Cancer Center member Terry Moore recently received the 2019 Rufus A. Lyman Award at the American Association of Colleges of Pharmacy annual meeting held in Chicago. The award recognizes the best paper published in the American Journal of Pharmaceutical Education in 2018. Moore, PhD, assistant professor of medicinal chemistry and pharmacognosy, served as co-author on the paper, “Assessing Students’…

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Docs should consider a patient’s weight before prescribing new chemotherapy drugs

A new class of cancer drugs just now entering the marketplace seems promising so far, but researchers at the University of Illinois at Chicago - led by University of Illinois Cancer Center member Paul Grippo - urge doctors to take into account a patient’s weight and liver status before prescribing them. The drugs are known as PI3K inhibitors, and they dramatically decrease the activation of a pathway commonly used by cancer cells to…

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Pauli recognized as UIC Distinguished Professor

University of Illinois Cancer Center member Guido Pauli, PhD, received the honorary title of UIC Distinguished Professor for the 2019-2020 academic year in the UIC College of Pharmacy. The designation was created to recognize faculty who have made significant impacts through scholarship, creativity and leadership. Pauli is a Norman. R. Farnsworth Professor of Pharmacognosy, associate director of the Institute for Tuberculosis Research, and director of the Program for Collaborative Research in the Pharmaceutical…

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